カエル味覚器内の副交感性神経終末の存在について

An investigation was made of the precise origin of the efferent nerve terminals in the fungiform papillae of the bullfrog\u27s tongue. Some axonal enlargements originate from the parasympathetic postganglionic neurons in the glossopharyngeal nerve. Axonal enlargements containing large dense-cored vesicles (100-120 nm in diameter) and small, clear synaptic vesicles (50-60 nm in diameter) were in close contact with the supporting cell in the taste disk. These results seem to provide morphological evidence for the existence of an efferent control system in the taste disk of the bullfrog

Development of a Wearable Robot for Assisting Carpentry Workers

The work of fitting ceiling boards is one of the hardest in carpentry, as it requires large muscular power. Hence there is a need to develop assisting apparatus for such work. In order to use this apparatus anywhere a wearable robot is the most suitable. As the robot must be autonomous and lightweight, a design requiring low power is proposed. A semi-active control method has been developed using springs, which requires low energy but satisfies the requirements of compliance and assistive force. In this paper several aspects of design, control and experiments of the developed prototype is explained. The experimental results prove that the robot reduces the muscular fatigue of carpentry worker by providing suitable assistive force

Predictive Modeling of Learning Continuation in Preschool Education Using Temporal Patterns of Development Tests

Learning analytics applies data analysis techniques to learning data in order to support students’ learning processes and to improve the quality of education. Despite the increasing attention to learning analytics for higher education, it has not been fully addressed in primary and preschool education. In this research, we apply learning analytics to preschool education to predict the continuation of learning of preschool children. Based on our hypothesis that temporal patterns in the assessment scores of development tests are effective features for prediction, we extract the temporal patterns using time-series clustering, and use them as the features of prediction models. The experimental results using a real preschool education dataset show that the use of the temporal patterns improves the predictive accuracy of future continuation of study

Polar localization and endocytic degradation of a boron transporter, BOR1, is dependent on specific tyrosine residues

Boron (B) is essential for plants, but is toxic in excess. Plants have to strictly regulate the uptake and translocation of B. In Arabidopsis thaliana root cells, a boric acid channel, NIP5;1, and a boric acid/borate exporter, BOR1, localize to the outer (facing soil) and inner plasma membrane domains, respectively, under B limitation. The opposite polar localizations of the importer and exporter would enable plant roots to transport B efficiently toward the xylem. In addition, accumulation of the B transporters is controlled by B conditions. When plants are shifted from low to high B conditions, NIP5;1 transcript accumulation is downregulated through mRNA degradation. The BOR1 protein is transported to the trans­Golgi network/early endosome and multivesicular body and finally degraded in the vacuole. We have recently shown that both the polar localization and the endocytic degradation of BOR1 are controlled by at least two tyrosine residues in a large loop located in the cytosol. We also showed that ubiquitination is required for the endocytic degradation of BOR1. Here, we analyzed possible involvement of an additional tyrosine residue (Y414) in the loop region and discuss the pathway of the BOR1 trafficking for polar localization and endocytic degradation of BOR1

Analysis of a Lipid/Polymer Membrane for Bitterness Sensing with a Preconditioning Process

It is possible to evaluate the taste of foods or medicines using a taste sensor. The taste sensor converts information on taste into an electrical signal using several lipid/polymer membranes. A lipid/polymer membrane for bitterness sensing can evaluate aftertaste after immersion in monosodium glutamate (MSG), which is called “preconditioning”. However, we have not yet analyzed the change in the surface structure of the membrane as a result of preconditioning. Thus, we analyzed the change in the surface by performing contact angle and surface zeta potential measurements, Fourier transform infrared spectroscopy (FTIR), X-ray photon spectroscopy (XPS) and gas cluster ion beam time-of-flight secondary ion mass spectrometry (GCIB-TOF-SIMS). After preconditioning, the concentrations of MSG and tetradodecylammonium bromide (TDAB), contained in the lipid membrane were found to be higher in the surface region than in the bulk region. The effect of preconditioning was revealed by the above analysis methods